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Any photo can use the Color Halftone filter as a cool novelty effect, but there are other techniques that you can use to give the effect of a comic book.
First, frame your picture on a neutral background, by using Layer Styles and choosing Stroke. Also add text boxes with big, stroked outlines for this effect, and use comic-style fonts for some extra authenticity. Finally, go to the Filter Gallery and choose Poster Edges for a finishing touch.